Senior Scientist - Oligo Bioinformatics

About this role

<p> </p><p><span style="font-size:12.0px"><span style="font-family:Verdana, Geneva, sans-serif">Work Location: Billerica, Massachusetts<br>Shift: No<br>Department: HC-RD-XO4 Oligonucleotide Chemical Conjugation<br>Recruiter: Beverly Dellisola</span></span></p><p><br><span style="font-size:12.0px"><span style="font-family:Verdana, Geneva, sans-serif"><strong>This information is for internals only. Please do not share outside of the organization.</strong></span></span></p><p> </p><br><p><span style="font-family: verdana, geneva, sans-serif;"><strong>Your Role:</strong></span></p><p><span style="font-family: verdana, geneva, sans-serif;">EMD Serono in Billerica, MA is seeking a Senior Scientist – Oligo Bioinformatics to add to their Oligonucleotide Therapeutics Group (DDTech).</span></p><p><span style="font-family: verdana, geneva, sans-serif;">Responsibilities:</span></p><ul type="disc"><li style="font-family: verdana, geneva, sans-serif;"><span style="font-family: verdana, geneva, sans-serif;">Utilize Bioinformatics platforms to design, evaluate and optimize siRNA sequences for targeted gene silencing</span></li><li style="font-family: verdana, geneva, sans-serif;"><span style="font-family: verdana, geneva, sans-serif;">Analyze gene expression data to identify suitable targets for siRNA/ASO development</span></li><li style="font-family: verdana, geneva, sans-serif;"><span style="font-family: verdana, geneva, sans-serif;">Work closely with chemists and biologists to integrate bioinformatics approaches into experimental workflow</span></li><li style="font-family: verdana, geneva, sans-serif;"><span style="font-family: verdana, geneva, sans-serif;">Perform transcriptome wide off-target prediction and annotation</span></li><li style="font-family: verdana, geneva, sans-serif;"><span style="font-family: verdana, geneva, sans-serif;">Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes</span></li></ul><p> </

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